Importantly, SNPs in the MS4A6A gene seems to selectively affect AD-related pathologies, since we did not observe significant correlation between MS4A6A SNPs and progranulin or α-synuclein levels, and only one SNP (rs7232) correlated with increased soluble TREM2 levels as previously reported [11, 12]. The gene discussed is GRN; the disease is Alzheimer disease.