These roles include regulating cell migration, neurite outgrowth, morphogenesis, apico-basal polarity, immune synapse modulation, phagocytosis, endocytosis, etc. To give a more detailed example, the Rab11 family member Rab25 was shown to mediate the formation of F-actin-rich filopodia-like protrusions to promote cancer cell invasive migration in the ovarian cancer cell line A2780 [33]. Here, RAB11A is linked to cancer.