Among the 3869 cases included across all the studies, 6 cases were reported as DCIS,3,8–10,16 10 cases were identified as invasive ductal carcinoma, 3,10,11,13,18,19 and 1 case was reported as Paget’s disease.4 Additionally, 42 cases of atypical lesions were documented, including ADH and ALH. This evidence concerns the gene AVP and ductal breast carcinoma in situ.