STING1 and acute kidney injury: Luo et al. reported that the cGAS-STING pathway is activated in a lipopolysaccharide (LPS)-induced mouse model of sepsis-associated acute kidney injury, and administration of the cGAS inhibitor RU.521 or the STING inhibitor DMXAA can alleviate renal damage in this model (Luo et al. 2024).