Conversely, when the complementarity is incomplete, translation is suppressed [95].In summary, miRNAs suppress PTEN by regulating the important PI3K/AKT pathway, thus promoting cell proliferation in many kinds of cancers, such as the following:Oral and gum cancer: It is one of the most common types of cancer worldwide and is characterized by difficulty in diagnosis and treatment [96]. This evidence concerns the gene AKT1 and cancer.