Acetylation stabilizes SIAH2 in gastric cancer cells.21,22 Testing immunoprecipitates that we formed with an anti-pan-acetylated lysine or SIAH2 antibodies, we found that FK228 induced acetylation of SIAH2 in HEL and K562 cells (Fig. 3d, e). Here, SIAH2 is linked to gastric cancer.