Gu et al. [38] found by microarray analysis and validation experiments that lncRNA BCYRN1 acts through the upregulation of NPRC, and that knockdown of lncRNA BCYRN1 contributed to a decrease in the levels of expression of NPRC, which itself has a pro-proliferative and anti-apoptotic function, thus, lncRNA BCYRN1 promotes proliferation and inhibits apoptosis of colorectal cancer cells by up-regulating NPRC. Here, NPR3 is linked to colorectal cancer.