In a recent [18F]fluorine-N,N-diethyl-2-(2-(4-(2-fluoroethoxy)phenyl)-5,7-dimethylpyrazolo[1,5a]pyrimidin-3-yl)acetamide ([18F]F-DPA714) PET/CT study of nonhuman primates (NHPs) infected with SARS-CoV-2, we determined a persistent increase in immune cell activation in the lungs and brain and detected TSPO expression, as a measure for macrophage activation, until day 30 after infection (11). The gene discussed is TSPO; the disease is infection.