CP and pancreatitis: It controls pancreatic growth and development and regulates the function of pancreatic islet β‐cells and α‐cells.[21, 46, 49] Although UCP2's role in the regulation of pancreatitis has not been directly reported[5, 50] its influence on metabolic reprogramming in pancreatic cancer is significant.[6] Our research is the first to identify UCP2 as a key gene mediating the transition from AP/SAP to CP.