CRISPR‐Cas9 genetic screeningClonogenic survival assaySA‐β‐gal stainingWestern blotting (CDC7, mTOR, apoptosis markers)Caspase‐3/7 apoptosis assayGene set enrichment analysisFlow cytometryIFRNA sequencingmTOR signaling assaysNeutral comet assayLive imaging of mitotic durationTumor volume measurement in xenograftsIHCMRI‐based tumor volume tracking. Here, MTOR is linked to neoplasm.