TNFSF10 and neoplasm: showed that inhibiting fatty acid transport protein 2 (FATP2) abrogates the activity of PMN‐MDSCs and substantially delays tumor progression.[179, 180] Moreover, TANs can inhibit T cell proliferation and induce T cell apoptosis through multiple molecules, such as reactive oxygen species (ROS), nitric oxide (NO), Fas ligand, and TRAIL.[185, 186, 187] These findings suggest that TANs suppress anti‐tumor immune responses through multiple mechanisms, including the formation of NETs and metabolic reprogramming.