IGFL2 and renal cell carcinoma: Addressing the critical challenge of drug resistance, Yihui Pan and colleagues (2023) identified IGFL2‐AS1, a long noncoding RNA overexpressed in sunitinib‐resistant RCC cells.[47] Their innovative approach involved developing chitosan‐coated solid lipid nanoparticles (∼247 nm) for the targeted delivery of ASO‐IGFL2‐AS1.