Lastly, chRCC is the type in which losses of whole chromosomes such as 1, 2, 6, 10, 13, 17, and 21 have been reported.[29] Most tumors in chRCC are sporadic, and familial forms include Birt‐Hogg‐Dubé (BHD) syndrome, which is linked to mutations in folliculin gene (FLCN). The gene discussed is FLCN; the disease is chromophobe renal cell carcinoma.