For example, rs2313171, the lead variant at the multitrait (CAD, colorectal cancer, whole blood, and tissue-specific PGAP3 expression) colocalized PGAP3 locus, was associated with 203 traits including fatty acid binding protein 9 (FDR P=4.91×10−110), white blood cell count (FDR P=9.41×10−51), aspartate aminotransferase (FDR P=1.23×10−40), and and HDL cholesterol levels (FDR P=1.66×10−38). This evidence concerns the gene PGAP3 and colorectal cancer.