In a multicenter cohort study, it was observed that CHI3L1/YKL-40 was significantly elevated in the serum of patients with DCM, and its levels correlated with markers of myocardial fibrosis (e.g., PIIINP) and myocardial scar area as detected via Cardiac Magnetic Resonance Imaging (CMR) (18). The gene discussed is CHI3L1; the disease is Myocardial fibrosis.