noted that a combined integer score of hs-cTnT, NT-proBNP, hs-CRP, and electrocardiogram (ECG)-diagnosed left ventricular hypertrophy (LVH, diagnosed by the Sokolow-Lyon criterion) was effective in stratifying the risk of HF in patients with DM and antecedent cardiovascular disease. This evidence concerns the gene CRP and hydrops fetalis.