qPCR detection confirmed that EHMT2 mRNA levels were significantly enhanced after T2DM-BMSCs transfection with the EHMT2 overexpression vector (p < 0.05) and overexpression of EHMT2 caused a decrease in LINC00657 (Figure 2D), consistent with the results regulated by UNC0638. This evidence concerns the gene EHMT2 and type 2 diabetes mellitus.