GSTM1 and Hypertension: Reports of autoimmune hemolytic anemia complicated by acute cerebral infarction are relatively rare.<h4>Case presentation</h4>We report a case of an 82-year-old female patient with hypertension who developed mixed-type AIHA complicated by acute cerebral infarction following intravenous infusion of ceftriaxone after erysipelas in which the patient's previous hemoglobin (Hb) level was maintained at approximately 108 g/L.