FN1 and neoplasm: In vivo, nanodrug MTI‐FDU displayed apparent suppression of tumor cells (Figure 4D) which reshaped the immune microenvironment through clearance of bacteria (Figure 4E) in the CRC spontaneous AD/Fn model, including promoting the infiltration of CD8+ T cells (Figure 4F) and reducing the secretion of inflammatory cytokines IL‐6 (Figure 4G) and IL‐22 (Figure 4H).