After a 60‐day exposure to a hypobaric hypoxia chamber simulating an altitude of 6000 m with 9.5 kPa atmospheric pressure, the rats indeed suffered from remarkable pathological cardiac hypertrophy (Figure 5B), both of which were confirmed by elevated ECG and UCG examinations (Figure 5C and Figure S9A–C) as well as increased serum levels of CTNI and CKMB (Figure 5D,E). The gene discussed is TNNI3; the disease is cardiac hypertrophy.