Hepatocellular carcinoma (Hep3B, Huh-7, HepG2), pancreatic adenocarcinoma (PANC-1, KLM-1, T3M4, MiaPaCa-2), and MCF-7 breast cancer cells exhibited strong B7-H6 positivity, contrasting with negative expression in SKBR-3, ZR75, and MDA-MB-231 lines. The gene discussed is NCR3LG1; the disease is hepatocellular carcinoma.