Many of the studies investigating cutaneous inflammatory and autoimmune processes have focused on T cell populations/subsets, with more recent data identifying ILC subsets within the skin that “mirror” their T helper cell counterparts, including in response to specific transcription factors (i.e., Th2 and ILC2 predominance in lesional skin of human and murine atopic dermatitis) (79, 92, 122, 244, 248). Here, CCL27 is linked to atopic eczema.