These includeFCGBP (18), GIMAP5 (19), WIPF1 (20), RASGEF1B (21), GIMAP7 (19), IGFLR1 (22), GPR35 (23), NCF1 (24), CLECL1 (25), HEXB (26) and IL10 (27) which may serve as important predictors of HNSCC in tumor microenvironment. The gene discussed is IL10; the disease is neoplasm.