Under co-culture conditions, after oncolytic virus infection of A673 and K562 cells (MOI=2 and MOI=5), the CD107a positivity rate of TCR-T cells was significantly increased (31.5% vs 0.13 for A 673, 56.96% vs 18.15% for K562) compared to the control group (without OVV-01 infection). The gene discussed is LAMP1; the disease is infection.