HLA-A*24:02 and HLA-B*15:02 are associated with increased risk of ASMs-induced SJS (OR = 3.60, 95% CI 1.21–10.72 and OR = 4.41, 95% CI 1.18–16.47, respectively).HLA-DRB1∗03:01 is associated with TEN (OR = 5.09; 95% CI 1.72–15.00).HLA-B∗40:02 is associated with DRESS (OR = 29.33; 95% CI 3.50–245.32) induced by ASMs. The gene discussed is HLA-B; the disease is Schwartz-Jampel syndrome.