Likewise, six studies found an association between HLA-B*15:02 and carbamazepine-induced SJS/TEN, four studies associated HLA-A*02:07, HLA-A*24:02, HLA-A*33:03, HLA-B*15:02, HLA-B*44:03 with lamotrigine-induced SCARs, one study associated HLA-A*02:01, HLA-B*35:01, HLA-C*04:01, and HLA-C*08:01 with lamotrigine- and phenytoin-induced SCARs. The gene discussed is HLA-B; the disease is toxic epidermal necrolysis.