By week 59, phenotype analysis of the SIINFEKL‐specific CD8+ T cells revealed a significant shift with ≈42% Tcm (0.5% out of 1.2%) and ≈58% Tem (0.7% out of 1.2%) (Figure 6E), indicating durable CD8+ T cell memory and phenotypic evolution over time.[53] Upon inoculation with B16F10‐OVA cells, the long‐lasting SIINFEKL‐specific memory CD8+ T cells effectively delayed tumor progression (Figure 6F,G). This evidence concerns the gene CD8A and neoplasm.