Our results also show a high prevalence of rare histotypes of FMC with positive PD-1 IHC scores both in iTILs (85%, 41/48) and sTILs (94%, 45/48), as reported in human breast cancer [44], human gastric carcinoma [45] and Hodgkin’s lymphoma [46]. Here, PDCD1 is linked to Hodgkins lymphoma.