GSK3B and multiple sclerosis: In an animal model of autoimmune encephalomyelitis, which mimics the pathogenesis of multiple sclerosis in humans, treatment with chrysin reduced histone deacetylase activity, levels of glycogen synthase kinase 3 beta (GSK-3β), IFN-γ, IL-17, TNF, and histone acetyltransferases HAT3 and HAT4—factors important in the analysis of neurological disease pathogenesis and neurogenesis [99].