KEGG and GO enrichment analyses revealed that core genes were significantly involved in multiple canonical immune- and apoptosis-related pathways, including the PI3K-Akt signaling pathway [51,52], apoptosis, Toll-like receptor signaling, the FoxO signaling pathway, and the p53 signaling pathway, as well as virus-associated pathways such as viral carcinogenesis, HTLV-1 infection, and human papillomavirus infection. Here, AKT1 is linked to human papilloma virus infection.