Peripheral monoterpenes display similar behaviour: α-pinene dampens hepatic TLR4/NF-κB signalling in Carbon tetrachloride (CCl4)-induced fibrosis, and tea tree-derived α-terpineol inhibits TLR4-triggered IL-1β and IL-6 production in human macrophages [54,55]. The gene discussed is TLR4; the disease is fibrosis.