SLC5A2 and Insulin resistance: In addition to these specific phytocannabinoids, Cannabis sativa also produces a substantial number of other phytocannabinoids, alongside terpenes and flavonoids, which contribute to its therapeutic potential against insulin resistance, diabetes, and its complications through synergistic “entourage effects” [12,13], further supporting a multi-mechanistic approach that may complement direct SGLT2 modulation.