SLC10A1 and infection: Infection with HDV generates intense type I IFN and ISG responses in differentiated HepaRG cells, HDV-infected primary human hepatocytes, and sodium taurocholate cotransporting polypeptide (NTCP)-overexpressing HepG2 and HepaRG cells, where the virus replication is largely induced by IFN-β and IFN-λ [25,36].