Another notable finding was the significantly higher urinary anti-S reactivity observed in vaccinated individuals with prior infection compared to those without, with the following results being obtained: for the eukaryotic S protein, G1 (0.3397 ± 0.04176) vs. G2 (0.7876 ± 0.08827), p < 0.0001; for the in-house S protein, G1 (0.3931 ± 0.03978) vs. G2 (0.6386 ± 0.06637), p < 0.0001. The gene discussed is PROS1; the disease is infection.