At the time of recruitment, the mean absolute CD4+ T-cell counts in the peripheral blood (cells/μL) of HIV-TB co-infected individuals were lower (mean ± SD: 166.7 ± 148.4 cells/μL) than that of HIV mono-infected individuals (mean ± SD: 308.9 ± 124.4 cells/μL), although the difference was statistically not significant (Figure 1A). This evidence concerns the gene CD4 and tuberculosis.