TNF and post-transplant lymphoproliferative disease: Co-cultivation of CAR-T and TRUCK cells with EBV (+) PTLD cells resulted in an increase in CAR-T activation markers, such as CD137 and CD25; in proinflammatory cytokines, including IFN-γ and tumor necrosis factor-α (TNF-α); and apoptosis-associated molecules (granzyme B and perforin), while IL-12 resulted in NK cell and monocyte recruitment.