STZ-induced type 1 diabetic mice show upregulated tubular injury markers including kidney injury molecule-1 (Kim-1), neutrophil gelatinase-associated lipocalin (Ngal), plasminogen activator inhibitor-1 (PAI-1), and β2-microglobulin (B2M) [80]. Here, SERPINE1 is linked to type 1 diabetes mellitus.