Twenty-five percent of participants had chronic kidney disease (CKD) stage 3 (eGFR 30–59 mL/min/1.73 m2); none had eGFR < 30 mL/min/1.73 m2, the mean eGFR was 58 ± 15 mL/min/1.73 m2, the median B-type natriuretic peptide was 380 pg/mL (IQR 210–600), and the mean C-reactive protein was 7.8 ± 4.2 mg/L (range 2.1–18.7 mg/L), consistent with low-grade systemic inflammation that is observed in patients with chronic HF. The gene discussed is CRP; the disease is chronic kidney disease.