BDNF and Insulin resistance: Tirani, Poursalehi [45] examined the relationship between the MIND diet and metabolic health status (hypertension, hypertriglyceridemia, hyperglycemia/insulin resistance, and chronic inflammation) relative to serum concentrations of brain-derived neurotrophic factor (BDNF) (a neurotrophic factor that may also play a role in systemic energy metabolism [71]).