Co-treatment AZA + BPHE30, which hyper-methylates three genes implicated in DNA repair, the pentose phosphate pathway, and xenobiotic detoxification, was, notably, also able to putatively block the expression of genes involved in autophagy, genotoxic-stress inducement, genomic instability, tumor pathogenesis, and dysfunction of peroxisomes, as well as promoting hypo-methylation of a gene coding for a cell-cycle regulator (Table 7). Here, RGCC is linked to neoplasm.