Cyp27a1 is polymorphic, but cyp27a1 SNPs (intronic rs17470271, intronic rs933994) were not found to be associated with a VD-associated disease (hepatitis) in a high-risk Chinese population, in contrast to cyp2r1 SNPs (rs12794714, intronic rs10741657, intronic rs1562902, and rs10766197), which were [58]. The gene discussed is CYP27A1; the disease is Hepatitis.