Within this scenario, copper ions play a multifaceted role, functioning not only as active sites in superoxide dismutase (SOD) enzymes but also contributing to metal-mediated oxidative stress associated with neurodegenerative diseases such as Alzheimer’s disease (AD), where they further promote the aggregation of β-amyloid peptides into toxic oligomers [23]. This evidence concerns the gene SOD1 and Alzheimer disease.