The groups treated with BRP and its isolated compound, maintained high IL-6 levels observed, even in the presence of parasitic infection compared to the infected/untreated BeWo cells (**** p < 0.0001); in contrast, SP-treated/infected BeWo cells downregulated IL-6 both in the absence and presence of T. gondii in relation to the untreated groups (*** p < 0.001) (Figure 4A). The gene discussed is IL6; the disease is parasitic infectious disease.