Ursolic acid is a pentacyclic triterpenoid that exhibits pro-apoptotic, anti-proliferative, anti-metastatic, and anti-angiogenic effects by modulating multiple oncogenic signaling pathways, including p53, Wnt/β-catenin, Ras, NF-κB, TRAIL, and STAT3, highlighting its potential as a multi-targeted therapeutic agent in cancer treatment [31,32]. Here, NFKB1 is linked to cancer.