As shown in Figure 7g,h, the proportion of tumor-infiltrating cytotoxic T cells (CD8+CD4−) in the MMSN@Dox treatment group significantly increased compared to that in the saline and other treatment groups, demonstrating a 2.74-fold and 1.46-fold elevation relative to the saline and Dox groups, respectively. The gene discussed is CD4; the disease is neoplasm.