Inhalable paclitaxel-in-liposome-in-bacteria system for primary lung cancer; demonstrated high lung targeting, enhanced cellular uptake (A549 cells), strong apoptosis induction (up to 98.6%), significant tumor suppression in lung cancer rat model, immune activation (↑ TNF-α, IL-4, IFN-γ), and selective lung biodistribution after pulmonary delivery... This evidence concerns the gene IFNG and lung carcinoma.