Neutrophil genes associated with a pro-tumour growth phenotype were also upregulated after the combination treatments compared to controls, including the CCL6 gene which promotes immunosuppressive networks, including anti-immune M2 macrophage polarisation [66], and tumour progression [67,68] and LILRB4 that has been associated with negative regulation of the immune response, antigen capture and presentation, and is a potential immunotherapy target [69,70]. This evidence concerns the gene LILRB4 and neoplasm.