Given that a negative prognostic impact of L1CAM expression was also reported in patients with ovarian cancer, single nucleotide polymorphisms (SNPs) of the L1CAM gene were sought in 103 ovarian cancer patients and 104 age-matched controls, finding that the genotype AA of one SNP in intron 1 was associated with ovarian cancer presence [27]. This evidence concerns the gene L1CAM and ovarian carcinoma.