CXCL8 and chorioamnionitis: However, there was a similar positive micro-organism rate in the women with sludge and those without (31.6% versus 38.4%), but a significantly higher level of amniotic fluid interleukin-8 (15.2 ng/mL vs. 5.8 ng/mL; p = 0.005) and a higher frequency of histological chorioamnionitis in those with sludge (52.6% vs. 23.3%; p = 0.01).