Differences were also observed in the classes of antihypertensive drugs prescribed, with renin–angiotensin system (RAS) inhibitors being more commonly used in HU patients (33.7% vs. 2.6%, p < 0.001), while nitrates were more frequently administered to participants with HE (31.3% vs. 13.0%, p = 0.001) (Figure 3). The gene discussed is REN; the disease is hereditary elliptocytosis.