When the ROC analysis was performed to evaluate the predictive value of the TG/HDL ratio and the other non-invasive parameters for NAFLD, the AUROC for the TG/HDL ratio was 0.682 (95% CI: 0.662–0.703), and this ratio outperformed the APRI (0.565), FIB-4 (0.591), and the ALT/AST ratio (0.668). This evidence concerns the gene GPT and metabolic dysfunction-associated steatotic liver disease.