For example, progesterone receptor-positive tumors had an ADC_map of 1171 ± 363 × 10−6 mm2/s versus 1075 ± 233 × 10−6 mm2/s in PR-negative cases; invasive lobular carcinomas averaged ADC_map = 1234 ± 542 × 10−6 mm2/s compared to 1110 ± 239 × 10−6 mm2/s in IDC; and grade 1 lesions showed ADC_map = 812 ± 106 × 10−6 mm2/s versus 1183 ± 385 and 1120 ± 240 in grades 2 and 3, respectively. This evidence concerns the gene PGR and invasive lobular breast carcinoma.