The patients were diagnosed with EMP by meeting the following criteria: the presence of one or more extramedullary plasma cell tumors, normal plasma cell density in the bone marrow with minimal morphological alterations or plasma cell infiltration below 10%, absence of radiological evidence of osteolysis, absence of hypercalcemia or renal failure, and low or absent serum M-protein levels. This evidence concerns the gene MYOM2 and hypercalcemia disease.